{"id":9,"date":"2010-12-07T17:59:26","date_gmt":"2010-12-07T17:59:26","guid":{"rendered":"http:\/\/whnlive.com\/solutions-template\/"},"modified":"2010-12-07T17:59:26","modified_gmt":"2010-12-07T17:59:26","slug":"cause","status":"publish","type":"page","link":"https:\/\/whnlive.com\/fatigue\/cause\/","title":{"rendered":"Cause"},"content":{"rendered":"<!--slice begin--><p>This <a href=\"http:\/\/en.wikipedia.org\/wiki\/Process_modeling\">process mod\u00adel<\/a> of fatigue relies on engi\u00adneer\u00ading prin\u00adci\u00adples based on mul\u00adti\u00adle <a href=\"http:\/\/en.wikipedia.org\/wiki\/Variable_(mathematics)\">vari\u00adant <\/a>sys\u00adtems and <a href=\"http:\/\/en.wikipedia.org\/wiki\/Control_theory\">Con\u00adtrol The\u00ado\u00adry<\/a>.<\/p>\n<p>Fatigue is cel\u00adlu\u00adlar dys\u00adfunc\u00adtion that occurs when a body\u2019s ener\u00adgy sup\u00adply fails to meet ongo\u00ading demand result\u00ading in an absence of ener\u00adgy, or tired\u00adness, as a result of dys\u00adfunc\u00adtion which affects inter\u00adde\u00adpen\u00addent aspects of cel\u00adlu\u00adlar ener\u00adgy sys\u00adtems.<\/p>\n<p>Per\u00adsis\u00adtent fatigue usu\u00adal\u00adly occurs with depen\u00addence of <a href=\"http:\/\/en.wikipedia.org\/wiki\/Cellular_respiration#Aerobic_respiration\">anaer\u00ado\u00adbic metab\u00ado\u00adlism<\/a> replaces nor\u00admal use of <a href=\"http:\/\/en.wikipedia.org\/wiki\/Aerobic_metabolism\">aer\u00ado\u00adbic metab\u00ado\u00adlism<\/a>:<\/p>\n<ul>\n<li>Aer\u00ado\u00adbic Metab\u00ado\u00adlism is effi\u00adcient and pro\u00adduces Car\u00adbon Diox\u00adide (38 ATP\/Glucose)&nbsp;is 19 times more effi\u00adcient;<\/li>\n<li>Than <a href=\"http:\/\/en.wikipedia.org\/wiki\/Anaerobic_respiration\">anaer\u00ado\u00adbic metab\u00ado\u00adlism<\/a> (2 ATP\/Glucose) and does not pro\u00adduce Car\u00adbon Diox\u00adide.<\/li>\n<\/ul>\n<p>Fatigue is the net effect of five con\u00adcur\u00adrent dys\u00adfunc\u00adtions which cre\u00adate a sta\u00adble equi\u00adlib\u00adri\u00adum of sus\u00adtained defi\u00adcien\u00adcy of cel\u00adlu\u00adlar ener\u00adgy. &nbsp;Click on each of these links to for fur\u00adther expla\u00adna\u00adtion:<\/p>\n<ul>\n<li><a href=\"http:\/\/whnlive.com\/fatigue\/cause\/krebs-cycle\/\">Krebs Cycle Dys\u00adfunc\u00adtion<\/a><\/li>\n<li><a href=\"http:\/\/whnlive.com\/fatigue\/cause\/anaerobic-lock\/\">Anaer\u00ado\u00adbic Lock<\/a><\/li>\n<li><a href=\"http:\/\/whnlive.com\/fatigue\/cause\/ph-dysregulation\/\">pH Dys\u00adreg\u00adu\u00adla\u00adtion<\/a><\/li>\n<li><a href=\"http:\/\/whnlive.com\/fatigue\/cause\/cellular-hypoxia\/\">Cel\u00adlu\u00adlar Hypox\u00adia<\/a><\/li>\n<li><a href=\"http:\/\/whnlive.com\/fatigue\/cause\/stable-equilibrium\/\">Sta\u00adble Equi\u00adlib\u00adri\u00adum<\/a><\/li>\n<\/ul>\n<p>Func\u00adtion\u00adal\u00adly, cel\u00adlu\u00adlar fatigue is the result of one or more con\u00adcur\u00adrent caus\u00ades:<\/p>\n<ul>\n<li><strong> Oxy\u00adgen Defi\u00adcien\u00adcy<\/strong> \u2014 where the body is unable to deliv\u00ader suf\u00adfi\u00adcient oxy\u00adgen forc\u00ading the cells from aer\u00ado\u00adbic to anaer\u00ado\u00adbic ener\u00adgy pro\u00adduc\u00adtion;<\/li>\n<li><strong>Deplet\u00aded Ener\u00adgy Metabo\u00adlites<\/strong> \u2014 where one or more nutri\u00adents required to main\u00adtain cel\u00adlu\u00adlar aer\u00ado\u00adbic metab\u00ado\u00adlism fails to meet ongo\u00ading demand;<\/li>\n<li><strong> Tox\u00adic Inter\u00adfer\u00adence<\/strong> \u2014 where one or more <a href=\"http:\/\/en.wikipedia.org\/wiki\/Toxin\">tox\u00adins<\/a> cre\u00adate durable inter\u00adfer\u00adence with cel\u00adlu\u00adlar ener\u00adgy pro\u00adduc\u00adtion.<\/li>\n<\/ul>\n<p>The rec\u00adog\u00adnized major\u00adi\u00adty of cel\u00adlu\u00adlar ener\u00adgy is pro\u00adduced by the mito\u00adchon\u00addria.<br>\nHere are addi\u00adtion\u00adal resources for fur\u00adther inves\u00adti\u00adga\u00adtion:<\/p>\n<ul>\n<li> <a href=\"http:\/\/en.wikipedia.org\/wiki\/Fatigue_(medical)\">Fatigue<\/a><\/li>\n<li> <a href=\"http:\/\/en.wikipedia.org\/wiki\/Mitochondrion\">Mito\u00adchon\u00addria<\/a><\/li>\n<li><a href=\"http:\/\/en.wikipedia.org\/wiki\/Mitochondrion\"><\/a><a href=\"http:\/\/www.mitochondrial-disorder-information.com\/what_is_mitochondria.html\" target=\"_blank\">What are Mito\u00adchon\u00addria<\/a><\/li>\n<li><a href=\"http:\/\/www.mitochondrial-disorder-information.com\/what_is_mitochondria.html\" target=\"_blank\"><\/a><a href=\"http:\/\/en.wikipedia.org\/wiki\/Fatigue_(medical)\">Fatigue<\/a><\/li>\n<li><a href=\"http:\/\/en.wikipedia.org\/wiki\/Fatigue_(medical)\"><\/a><a href=\"http:\/\/library.whnlive.com\/Mitochondria\">Mito\u00adchon\u00addria Research Library<\/a> \/&nbsp;<a href=\"http:\/\/www.mitochondrial-disorder-information.com\/mitochondrial_ebooks.html\">Source<\/a><\/li>\n<\/ul>\n<!--slice end-->","protected":false},"excerpt":{"rendered":"<p>This process mod\u00adel of fatigue relies on engi\u00adneer\u00ading prin\u00adci\u00adples based on mul\u00adti\u00adle vari\u00adant sys\u00adtems and Con\u00adtrol The\u00ado\u00adry. Fatigue is cel\u00adlu\u00adlar dys\u00adfunc\u00adtion that occurs when a body\u2019s ener\u00adgy sup\u00adply fails to meet ongo\u00ading demand result\u00ading in an absence of ener\u00adgy, or tired\u00adness, as a result of dys\u00adfunc\u00adtion which affects inter\u00adde\u00adpen\u00addent aspects of cel\u00adlu\u00adlar ener\u00adgy sys\u00adtems. Per\u00adsis\u00adtent \u2026 <\/p>\n<p><a class=\"more-link btn\" href=\"https:\/\/whnlive.com\/fatigue\/cause\/\">Con\u00adtin\u00adue read\u00ading<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"open","ping_status":"open","template":"","meta":{"wp_typography_post_enhancements_disabled":false,"footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry","nodate","item-wrap"],"_links":{"self":[{"href":"https:\/\/whnlive.com\/fatigue\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/whnlive.com\/fatigue\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/whnlive.com\/fatigue\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/whnlive.com\/fatigue\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/whnlive.com\/fatigue\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":0,"href":"https:\/\/whnlive.com\/fatigue\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"wp:attachment":[{"href":"https:\/\/whnlive.com\/fatigue\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}