Can the reservoir be over filled or burst if I continue to run my Air Separator?

No, the reser­voir is designed to hold a pas­sive vol­ume. It does not get pres­sur­ized or fill beyond that capac­i­ty. If your air sep­a­ra­tor con­tin­ues to run the reser­voir will vent the excess vol­ume into the room. This does not cause any harm to the sys­tem and is one of the attrib­ut­es of the design allow­ing unat­tend­ed fill­ing with­out a risk of over­fill­ing the reser­voir.