Is it possible to cause oxidative stress to lungs with LiveO2 or ExtremeO2?

Oxidative Stress to Lungs

The LiveO2 and ExtremeO2 equip­ment is not capa­ble of deliv­er­ing enough oxy­gen for long enough to dam­age lungs or cause oxy­gen tox­i­c­i­ty.

There are two doc­u­ment­ed sit­u­a­tions where low pres­sure oxy­gen can cause harm:

  • Lorrain Smith Effect — Resulting from oxida­tive stress to lung tis­sues exceed­ing 95% for four hours
  • Paul Bert Effect — Oxygen Toxicity — with high pres­sure caus­es See: Oxygen Toxicity in Man

At nor­mal pres­sure, the med­ical­ly accept­ed thresh­old for oxida­tive stress to the lungs requires oxy­gen in excess of 95% exceed­ing 4 hours in the most sen­si­tive indi­vid­u­als, with symp­toms typ­i­cal­ly appear­ing after 14 hours. See: Bench to Bedside Review: Oxygen as a Drug

LiveO2 is capa­ble of high lev­els 50 l/min for about 15 min­utes. This use is far below both thresh­olds for oxida­tive stress:

  • The con­cen­tra­tion of oxy­gen is at about 80%
  • The dura­tion is oxy­gen use is for 15 min­utes max­i­mum until con­sump­tion exhausts the reser­voir, and use must stop.

All sys­tems, includ­ing LiveO2, can only deliv­er oxy­gen well with­in known safe lev­els, of both time and dura­tion.