Anaerobic metabolism occurs when the oxygen supply is unable to deliver enough oxygen to maintain aerobic energy production. It is a supply versus demand system. See Cause for other factors.
Demand exceeds supply when either:
- Burst Demand occurs when there is a temporary demand increase that exceeds oxygen supply – under short term burst-exertion conditions;
- Cellular Hypoxia occurs when there is prolonged deficiency due to dysfunction of the oxygen delivery, or nutrient substrate required to maintain aerobic metabolism becomes durably deplete.
A demand condition that overwhelms the primary and secondary system reserves may create durable cellular hypoxia by triggering inflammation in cells that line the vascular system, endothelium. Cellular inflammation occurs when cellular sodium replaces potassium, resulting in enlarged regions of polarized water around sodium ions, which in turn compel the cell to absorb water inflate.
The inflation reduces the diameter of the capillary and limits or prevents passage of erythrocytes, red blood cells, through the capillary. Limited erythrocytes, limit oxygen, which is needed to reverse the inflammation, so the condition remains fixed — and cellular hypoxia becomes durable.
Durable hypoxia occurs when a hypoxic or stress episode triggers other effects, capillary choke mechanism (Ardenne), that inhibits the oxygen delivery process in an unrecoverable (under normal metabolism). This effect is fully described in Chapter-1: Oxygen Multistep Therapy, Ardenne.
The durable nature of the capillary choke makes it a dominant factor in all fatigue and acid related dysfunctions because it creates a durable blockage to blood flow and oxygen delivery.
This author asserts it is a dominant cause of Anaerobic Lock.
In most cases, cellular energy production is heavily dependent on anaerobic glycolysis for ongoing performance, resulting in:
- Energy Deficiency / Fatigue
- Overproduction of lactic acid
- Carbon Dioxide Deficiency which causes blood acid/alkali instability:
- pH Imbalance inhibits oxygen transport in blood
- Creating interdependent dysfunctions